Serum Hepcidin Concentration in Relation to Iron Deficiency inAin Shams Athletes

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Serum hepcidin levels and iron parameters in children with iron deficiency

BACKGROUND Iron deficiency (ID) and iron deficiency anemia (IDA) are common nutritional disorders in children. Hepcidin, a peptide hormone produced in the liver, is a central regulator of systemic iron metabolism. We evaluated whether serum hepcidin levels can diagnose ID in children. METHODS Sera from 59 children (23 males and 36 females; 5 months to 17 years) were analyzed for hepcidin-25 b...

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Combinatorial effects of malaria season, iron deficiency, and inflammation determine plasma hepcidin concentration in African children.

Hepcidin is the master regulatory hormone that governs iron homeostasis and has a role in innate immunity. Although hepcidin has been studied extensively in model systems, there is less information on hepcidin regulation in global health contexts where iron deficiency (ID), anemia, and high infectious burdens (including malaria) all coexist but fluctuate over time. We evaluated iron status, hep...

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Iron Deficiency in Female Adolescent Athletes

Background: Iron deficiency (ID) is a very common condition and the most common nutritional deficiency in the world. ID mostly affects females, both athletes and non-athletes. Several underlying mechanisms are identified, such as insufficient dietary intake and losses by menses. In the athlete group different additional mechanisms are discussed including the existence of “sports anaemia” and in...

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Decreased Serum Hepcidin Concentration Correlates with Brain Iron Deposition in Patients with HBV-Related Cirrhosis

PURPOSE Excessive brain iron accumulation contributes to cognitive impairments in hepatitis B virus (HBV)-related cirrhotic patients. The underlying mechanism remains unclear. Hepcidin, a liver-produced, 25-aminoacid peptide, is the major regulator of systemic iron metabolism. Abnormal hepcidin level is a key factor in some body iron accumulation or deficiency disorders, especially in those ass...

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ژورنال

عنوان ژورنال: The Medical Journal of Cairo University

سال: 2021

ISSN: 2536-9806

DOI: 10.21608/mjcu.2021.153786